P02-020 - CAPS in Turkish children: treatment with ANTI IL1
نویسندگان
چکیده
منابع مشابه
P02-020 - CAPS in Turkish children: treatment with ANTI IL1
Case Report Results All of our patients had symptoms within the first 3 months of life. All had fever, urticaria and persistant labaratory inflammation. All except one patient had failure to thrive. Except for the one patient with Muckle Wells syndrome all had neurological features ranging from headache to convulsions, hydrocephalus, cognitive dysfunction.Two patients, one without a mutation, h...
متن کاملP02-033 - CAPS diagnosis and treatment in an Israeli family
Case Report We confirmed the Muckle-Wells syndrome phenotype of CAPS by NLRP3 genetic testing in a three generation family of Turkish Jewish origin, previously diagnosed with familial Behcet disease due to the presence of mucosal ulcers in several family members with the finding of the HLA-B51 antigen in at least one family member. Eight family members including a deceased grandfather, 4 of his...
متن کاملP02-029 - CAPS or SJIA
Case Report The patient became ill when she was 3 years old. She had fever, rash and artralgia and pericarditis. After examination in hospital she was diagnosed sJIA. She took glucocorticosteroids 1 mg/kg daily per os, methylprednisolone 10 mg/kg IV, No3, and MTX 10mg/m2/week with positive results. She took that therapy during 2 years. When the dose of GC decreased she had flares (fever, rash, ...
متن کاملPW03-020 – A decade of ANTI-IL-1 therpay for CAPS in the UK
Results Of 82 patients with clinical CAPS a pathogenic sequence variant (PSV) was detected in 77 (94%); 17 PSVs were identified, the commonest were R260W (27%), A439V (23%), T348M (17%), V198M (5%). 5 patients had no PSV detected on Sanger sequencing: 3 children with CINCA and 2 patients with adult onset clinical MWS. 90% were white, 8.5% South Asian and 1% African. 46 (56%) gave a positive fam...
متن کاملO 23: Anti-Inflammatory Treatment in Children with Refractory Seizure
Epilepsy is a neurological disease of the central nervous system. It is estimated that about 50-70 million people worldwide suffer from this chronic disorder and 20 to 30% are resistant to conventional anti-epileptic drugs. In the epilepsy therapeutic arena, there is real need for developing novel antiepileptogenesis treatments that offer a way to prevent the onset or the progression of the dis...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s1-a127